Think small. Think really, really small—smaller than anything you ever saw through a microscope at school.
Think atoms and molecules, and now you’re there. You’re down at the nanoscale, where scientists are learning about these fundamental components of matter and are putting them to use in beneficial ways.
Cannabidiol has high activity in the body but low bioavailability, according to the study by Mechoulam R et al., published on Journal of Clinical Pharmacology, the bioavailability when being used orally is only 13-19%, while being used nasally (inhalantly) is about 31%. It is quickly metabolized, and the half-life is within about 9 hours.
CBD is well absorbed after being administered orally, and has high activity in the body but low bioavailability. Thus, it is very necessary to improve the ability of absorption, increase the bioavailability of the agent.
Applying nano technologies is a novel technological application for generating vehicle systems and increasing the bioavailability of the agent. In particular, the application of a liposome system, which is a new system having the structure composed of sphere subunits and very small dimensions (nano-sized), is capable of containing, protecting, transporting and releasing active agents to desired sites of the body exactly and with proper dosages.
Cannabidiol packaged in nano-vehicle systems helps transport an agent to targets in a selectively, effectively and drug-saving way. Exactly how all of Kokonola's products are produced.
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"Nano-science and Nano-technology are the study and application of extremely small things and can be used across all the other science fields, such as chemistry, biology, physics, materials science, and engineering.
Today's scientists and engineers are finding a wide variety of ways to deliberately make materials at the Nano-scale to take advantage of their enhanced properties such as higher strength, lighter weight, increased control of light spectrum, and greater chemical reactivity than their larger-scale counterparts."
Nano-technology is helping to considerably improve, even revolutionize, many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others.
Many benefits of nanotechnology depend on the fact that it is possible to tailor the structures of materials at extremely small scales to achieve specific properties, thus greatly extending the materials science toolkit. Using nanotechnology, materials can effectively be made stronger, lighter, more durable, more reactive, more sieve-like, or better electrical conductors, among many other traits. Many everyday commercial products are currently on the market and in daily use that rely on nanoscale materials and processes.
Nano-Technology is already broadening the medical tools, knowledge, and therapies currently available to clinicians. Nano-Medicine, the application of nanotechnology in medicine, draws on the natural scale of biological phenomena to produce precise solutions for disease prevention, diagnosis, and treatment.
Today, nanotechnology impacts human life every day. The potential benefits are many and diverse. However, because of extensive human exposure to nanoparticles, there is a significant concern about the potential health and environmental risks.
These concerns led to the emergence of additional scientific disciplines including nanotoxicology and nanomedicine. Nanotoxicology is the study of potential adverse health effects of nanoparticles.
Nanomedicine, which includes subsectors such as tissue engineering, biomaterials, biosensors, and bioimaging, was developed to study the benefits and risks of nanomaterials used in medicine and medical devices.
Some of the potential benefits of medical nanomaterials include improved drug delivery, antibacterial coatings of medical devices, reduced inflammation, better surgical tissue healing, and detection of circulating cancer cells.
Nanotechnology is one of the most exciting and fast-moving areas of science today. In the food area, researchers are working with nanotechnology to create novel products that may be of benefit to health and diets. What are their possible applications? Is it safe?