A brief look into the world of CBD's
A Cannabinoid is one of a class of diverse chemical compounds found in cannabis. There are at least 113 different cannabinoids isolated from cannabis, which exhibit varied effects. Below are some of the more popular ones:
- THC (Tetrahydrocannabinol) is the primary psychoactive component of the Cannabis plant. These cannabinoids produce the effects associated with cannabis by binding to the CB1 cannabinoid receptors in the brain.
- CBD (Cannabidiol) is the non-psychoactive component of the Cannabis plant. Recent evidence shows that the compound counteracts cognitive impairment associated with the use of cannabis. There is now strong evidence that CBD treats chronic pain, and it is used by many in the form of a topical oil treatment.
- CBN (Cannabinol) is the primary product of THC degradation, and there is usually little of it in a fresh plant. CBN content increases as THC degrades in storage, and with exposure to light and air. It is only mildly psychoactive. Its affinity to the CB2 receptor is higher than for the CB1 receptor.
- CBG (Cannabigerol) is non-psychoactive but still contributes to the overall effects of Cannabis. CBG has been shown to promote cell death in cancer cells and inhibit tumor growth in mice. It also binds to the CB2 receptor.
- THCV (Tetrahydrocannabivarin) is prevalent in certain central Asian and southern African strains of Cannabis. It competes with THC at CB1 receptors and lessens the psychoactive effects of THC.
- CBC (Cannabichromene) is non-psychoactive and does not affect the psychoactivity of THC. CBC has shown anti-tumor effects in breast cancer xenoplants in mice. More common in tropical cannabis varieties.
Cannabinoid Receptors, there are two known types of cannabinoid receptors. Cannabinoids interact with specific membrane receptors. These receptors are common in mammals.
- CB1 (Cannabinoid receptor 1) is found primarily in the brain and in both male and female reproductive systems. Also found in the anterior eye and retina.
- CB2 (Cannabinoid receptor 2) is found in the immune system and parts of the nervous system.
Endocannabinoid System (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors. Endocannabinoids are substances produced from within the body that activate cannabinoid receptors. Endocannabinoids serve as intercellular lipid messengers, signaling molecules that are released from one cell and activating the cannabinoid receptors present on other nearby cells.
This Chart shows how different cannabinoids interact with different ailments or sicknesses.